Dasatinib Plus Quercetin Alleviates Choroid Neovascularization by Reducing the Cellular Senescence Burden in the RPE–Choroid

PURPOSE: Wet AMD (wAMD) is associated with cellular senescence. However, senescent cell–targeted therapies for wAMD have rarely been comprehensively studied. This study aimed to explore the therapeutic effects of senolytic agents on choroidal neovascularization (CNV). METHODS: RNA sequencing dataset...

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Detalles Bibliográficos
Autores principales: Wang, Yinhao, Tseng, Yulin, Chen, Keyu, Chen, Kuangqi, Chen, Kai, Huang, Zhihua, Mao, Zebin, Li, Xuemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Retina
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541238/
https://www.ncbi.nlm.nih.gov/pubmed/37750741
http://dx.doi.org/10.1167/iovs.64.12.39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541238/
https://www.ncbi.nlm.nih.gov/pubmed/37750741
http://dx.doi.org/10.1167/iovs.64.12.39

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