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Cancer-associated fibroblast-related prognostic signature predicts prognosis and immunotherapy response in pancreatic adenocarcinoma based on single-cell and bulk RNA-sequencing

Cancer-associated fibroblasts (CAFs) influence many aspects of pancreatic adenocarcinoma (PAAD) carcinogenesis, including tumor cell proliferation, angiogenesis, invasion, and metastasis. A six-gene prognostic signature was constructed for PAAD based on the 189 CAF marker genes identified in single-...

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Detalles Bibliográficos
Autores principales: Chen, Yajun, Deng, Qican, Chen, Hui, Yang, Jianguo, Chen, Zhenzhou, Li, Juncai, Fu, Zhongxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541448/
https://www.ncbi.nlm.nih.gov/pubmed/37775715
http://dx.doi.org/10.1038/s41598-023-43495-y