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Cancer-associated fibroblast-related prognostic signature predicts prognosis and immunotherapy response in pancreatic adenocarcinoma based on single-cell and bulk RNA-sequencing
Cancer-associated fibroblasts (CAFs) influence many aspects of pancreatic adenocarcinoma (PAAD) carcinogenesis, including tumor cell proliferation, angiogenesis, invasion, and metastasis. A six-gene prognostic signature was constructed for PAAD based on the 189 CAF marker genes identified in single-...
Autores principales: | Chen, Yajun, Deng, Qican, Chen, Hui, Yang, Jianguo, Chen, Zhenzhou, Li, Juncai, Fu, Zhongxue |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541448/ https://www.ncbi.nlm.nih.gov/pubmed/37775715 http://dx.doi.org/10.1038/s41598-023-43495-y |
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