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Phase-shifting the circadian glucocorticoid profile induces disordered feeding behaviour by dysregulating hypothalamic neuropeptide gene expression

Here we demonstrate, in rodents, how the timing of feeding behaviour becomes disordered when circulating glucocorticoid rhythms are dissociated from lighting cues; a phenomenon most commonly associated with shift-work and transmeridian travel ‘jetlag’. Adrenalectomized rats are infused with physiolo...

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Detalles Bibliográficos
Autores principales: Yoshimura, Mitsuhiro, Flynn, Benjamin P., Kershaw, Yvonne M., Zhao, Zidong, Ueta, Yoichi, Lightman, Stafford L., Conway-Campbell, Becky L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541449/
https://www.ncbi.nlm.nih.gov/pubmed/37775688
http://dx.doi.org/10.1038/s42003-023-05347-3