Statistical methods and data visualisation of patient-reported outcomes in early phase dose-finding oncology trials: a methodological review

BACKGROUND: Traditionally, within dose-finding clinical trials, treatment toxicity and tolerability are assessed by clinicians. Research has shown that clinician reporting may have inadequate inter-rater reliability, poor correlation with patient reported outcomes, and under capture the true toxicit...

Descripción completa

Detalles Bibliográficos
Autores principales: Alger, Emily, Minchom, Anna, Lee Aiyegbusi, Olalekan, Schipper, Matthew, Yap, Christina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541462/
https://www.ncbi.nlm.nih.gov/pubmed/37781154
http://dx.doi.org/10.1016/j.eclinm.2023.102228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541462/
https://www.ncbi.nlm.nih.gov/pubmed/37781154
http://dx.doi.org/10.1016/j.eclinm.2023.102228

Ejemplares similares