Association of Cytochrome P450 2E1 and N-Acetyltransferase 2 Genotypes with Serum Isoniazid Level and Anti-Tuberculosis Drug-Induced Hepatotoxicity: A Cross-Sectional Study

BACKGROUND: Anti-tuberculosis drug-induced hepatotoxicity can result from genetic polymorphism of the isoniazid (INH) metabolizing enzyme. This study aimed to determine the effect of genetic polymorphism of N-acetyltransferase 2 (NAT2) and cytochrome P450 2E1 (CYP2E1) genes on serum isoniazid level...

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Detalles Bibliográficos
Autores principales: Pourmohamadi, Nasir, Pour Abdollah Toutkaboni, Mihan, Hayati Roodbari, Nasim, Tabarsi, Payam, Baniasadi, Shadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University of Medical Sciences 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541540/
https://www.ncbi.nlm.nih.gov/pubmed/37786472
http://dx.doi.org/10.30476/ijms.2023.96145.2765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541540/
https://www.ncbi.nlm.nih.gov/pubmed/37786472
http://dx.doi.org/10.30476/ijms.2023.96145.2765

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