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Context-dependent hyperactivity in syngap1a and syngap1b zebrafish autism models

BACKGROUND AND AIMS: SYNGAP1 disorder is a prevalent genetic form of Autism Spectrum Disorder and Intellectual Disability (ASD/ID) and is caused by de novo or inherited mutations in one copy of the SYNGAP1 gene. In addition to ASD/ID, SYNGAP1 disorder is associated with comorbid symptoms including t...

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Detalles Bibliográficos
Autores principales: Sumathipala, Sureni H., Khan, Suha, Kozol, Robert A., Araki, Yoichi, Syed, Sheyum, Huganir, Richard L., Dallman, Julia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541574/
https://www.ncbi.nlm.nih.gov/pubmed/37786701
http://dx.doi.org/10.1101/2023.09.20.557316