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A spatially mapped gene expression signature for intestinal stem-like cells identifies high-risk precursors of gastric cancer

OBJECTIVE: Gastric intestinal metaplasia (GIM) is a precancerous lesion that increases gastric cancer (GC) risk. The Operative Link on GIM (OLGIM) is a combined clinical-histopathologic system to risk-stratify patients with GIM. The identification of molecular biomarkers that are indicators for adva...

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Detalles Bibliográficos
Autores principales: Huang, Robert J., Wichmann, Ignacio A., Su, Andrew, Sathe, Anuja, Shum, Miranda V., Grimes, Susan M., Meka, Rithika, Almeda, Alison, Bai, Xiangqi, Shen, Jeanne, Nguyen, Quan, Amieva, Manuel R., Hwang, Joo Ha, Ji, Hanlee P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541579/
https://www.ncbi.nlm.nih.gov/pubmed/37786704
http://dx.doi.org/10.1101/2023.09.20.558462