Cargando…

Label-free, real-time monitoring of membrane binding events at zeptomolar concentrations using frequency-locked optical microresonators

Binding events to elements of the cell membrane act as receptors which regulate cellular function and communication and are the targets of many small molecule drug discovery efforts for agonists and antagonists. Conventional techniques to probe these interactions generally require labels and large a...

Descripción completa

Detalles Bibliográficos
Autores principales: Gin, Adley, Nguyen, Phuong-Diem, Melzer, Jeffrey E., Li, Cheng, Strzelinski, Hannah, Liggett, Stephen B., Su, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541581/
https://www.ncbi.nlm.nih.gov/pubmed/37786702
http://dx.doi.org/10.1101/2023.09.20.558657