HRMAS (13)C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile

Stickland-fermenting Clostridia preferentially ferment amino acids to generate energy and anabolic substrates for growth. In gut ecosystems, these species prefer dual redox substrates, particularly mucin-abundant leucine. Here, we establish how theronine, a more prevalent, mucinabundant substrate, s...

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Detalles Bibliográficos
Autores principales: Pavao, Aidan, Zhang, Ella, Monestier, Auriane, Peltier, Johann, Dupuy, Bruno, Cheng, Leo, Bry, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541586/
https://www.ncbi.nlm.nih.gov/pubmed/37786668
http://dx.doi.org/10.1101/2023.09.18.558167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541586/
https://www.ncbi.nlm.nih.gov/pubmed/37786668
http://dx.doi.org/10.1101/2023.09.18.558167

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