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HRMAS (13)C NMR and genome-scale metabolic modeling identify threonine as a preferred dual redox substrate for Clostridioides difficile
Stickland-fermenting Clostridia preferentially ferment amino acids to generate energy and anabolic substrates for growth. In gut ecosystems, these species prefer dual redox substrates, particularly mucin-abundant leucine. Here, we establish how theronine, a more prevalent, mucinabundant substrate, s...
Autores principales: | Pavao, Aidan, Zhang, Ella, Monestier, Auriane, Peltier, Johann, Dupuy, Bruno, Cheng, Leo, Bry, Lynn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541586/ https://www.ncbi.nlm.nih.gov/pubmed/37786668 http://dx.doi.org/10.1101/2023.09.18.558167 |
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