Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment

New approaches for combatting microbial infections are needed. One strategy for disrupting pathogenesis involves developing compounds that interfere with bacterial virulence. A critical molecular determinant of virulence for Gram-negative bacteria are efflux pumps of the resistance-nodulation-divisi...

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Detalles Bibliográficos
Autores principales: Allgood, Samual C., Su, Chih-Chia, Crooks, Amy L., Meyer, Christian T., Zhou, Bojun, Betterton, Meredith D., Barbachyn, Michael R., Yu, Edward W., Detweiler, Corrella S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541609/
https://www.ncbi.nlm.nih.gov/pubmed/37786697
http://dx.doi.org/10.1101/2023.09.20.558466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541609/
https://www.ncbi.nlm.nih.gov/pubmed/37786697
http://dx.doi.org/10.1101/2023.09.20.558466

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