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Bacterial Efflux Pump Modulators Prevent Bacterial Growth in Macrophages and Under Broth Conditions that Mimic the Host Environment
New approaches for combatting microbial infections are needed. One strategy for disrupting pathogenesis involves developing compounds that interfere with bacterial virulence. A critical molecular determinant of virulence for Gram-negative bacteria are efflux pumps of the resistance-nodulation-divisi...
Autores principales: | Allgood, Samual C., Su, Chih-Chia, Crooks, Amy L., Meyer, Christian T., Zhou, Bojun, Betterton, Meredith D., Barbachyn, Michael R., Yu, Edward W., Detweiler, Corrella S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541609/ https://www.ncbi.nlm.nih.gov/pubmed/37786697 http://dx.doi.org/10.1101/2023.09.20.558466 |
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