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Cohesin mediated loop extrusion from active enhancers form chromatin jets in C. elegans
In mammals, cohesin and CTCF organize the 3D genome into topologically associated domains (TADs) to regulate communication between cis-regulatory elements. However, many organisms, including S. cerevisiae, C. elegans, and A. thaliana lack CTCF. Here, we use C. elegans as a model to investigate the f...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Cold Spring Harbor Laboratory
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541618/ https://www.ncbi.nlm.nih.gov/pubmed/37786717 http://dx.doi.org/10.1101/2023.09.18.558239 |