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Structure of RADX and mechanism for regulation of RAD51 nucleofilaments

Replication fork reversal is a fundamental process required for resolution of encounters with DNA damage. A key step in the stabilization and eventual resolution of reversed forks is formation of RAD51 nucleoprotein filaments on exposed ssDNA. To avoid genome instability, RAD51 filaments are tightly...

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Detalles Bibliográficos
Autores principales: Balakrishnan, Swati, Adolph, Madison, Tsai, Miaw-Sheue, Gallagher, Kaitlyn, Cortez, David, Chazin, Walter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541619/
https://www.ncbi.nlm.nih.gov/pubmed/37786681
http://dx.doi.org/10.1101/2023.09.19.558089