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A Humanized Yeast System for Evaluating the Protein Prenylation of a Wide Range of Human and Viral CaaX Sequences

The C-terminal CaaX sequence (cysteine-aliphatic-aliphatic-any of several amino acids) is subject to isoprenylation on the conserved cysteine and is estimated to occur in 1–2% of proteins within yeast and human proteomes. Recently, non-canonical CaaX sequences in addition to shorter and longer lengt...

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Detalles Bibliográficos
Autores principales: Hildebrandt, Emily R., Sarkar, Anushka, Ravishankar, Rajani, Kim, June H., Schmidt, Walter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541624/
https://www.ncbi.nlm.nih.gov/pubmed/37786692
http://dx.doi.org/10.1101/2023.09.19.558494