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Unraveling the Structure of Meclizine Dihydrochloride with MicroED
Meclizine (Antivert, Bonine) is a first-generation H1 antihistamine used in the treatment of motion sickness and vertigo. Despite its wide medical use for over 70 years, its crystal structure and the details of protein-drug interactions remained unknown. In this study, we used microcrystal electron...
Autores principales: | Lin, Jieye, Unge, Johan, Gonen, Tamir |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541648/ https://www.ncbi.nlm.nih.gov/pubmed/37786674 http://dx.doi.org/10.1101/2023.09.05.556418 |
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