Cytosine–phosphate–guanine oligodeoxynucleotides alleviate radiation-induced kidney injury in cervical cancer by inhibiting DNA damage and oxidative stress through blockade of PARP1/XRCC1 axis

BACKGROUND: Radiotherapy can cause kidney injury in patients with cervical cancer. This study aims to investigate the possible molecular mechanisms by which CpG-ODNs (Cytosine phosphate guanine-oligodeoxynucleotides) regulate the PARP1 (poly (ADP-ribose) polymerase 1)/XRCC1 (X-ray repair cross-compl...

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Detalles Bibliográficos
Autores principales: Zhang, Deyu, Zhang, Shitai, He, Zheng, Chen, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541701/
https://www.ncbi.nlm.nih.gov/pubmed/37773127
http://dx.doi.org/10.1186/s12967-023-04548-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541701/
https://www.ncbi.nlm.nih.gov/pubmed/37773127
http://dx.doi.org/10.1186/s12967-023-04548-y

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