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Translational assessment of a DATA-functionalized FAP inhibitor with facile (68)Ga-labeling at room temperature

PURPOSE: The present study aims at evaluating the preclinical and the clinical performance of [(68)Ga]Ga-DATA(5m.)SA.FAPi, which has the advantage to be labeled with gallium-68 at room temperature. METHODS: [(68)Ga]Ga-DATA(5m).SA.FAPi was assessed in vitro on FAP-expressing stromal cells, followed b...

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Detalles Bibliográficos
Autores principales: Escudero-Castellanos, Alondra, Kurth, Jens, Imlimthan, Surachet, Menéndez, Elena, Pilatis, Eirinaios, Moon, Euy Sung, Läppchen, Tilman, Rathke, Hendrik, Schwarzenböck, Sarah M., Krause, Bernd J., Rösch, Frank, Rominger, Axel, Gourni, Eleni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541845/
https://www.ncbi.nlm.nih.gov/pubmed/37284857
http://dx.doi.org/10.1007/s00259-023-06285-2