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Recent studies of the molecular mechanism of lusitropy due to phosphorylation of cardiac troponin I by protein kinase A
Ca(2+) acts on troponin and tropomyosin to switch the thin filament on and off, however in cardiac muscle a more graded form of regulation is essential to tailor cardiac output to the body’s needs. This is achieved by the action of adrenaline on β1 receptors of heart muscle cells leading to enhanced...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541847/ https://www.ncbi.nlm.nih.gov/pubmed/36131171 http://dx.doi.org/10.1007/s10974-022-09630-4 |