Establishment of a 96-well transwell system using primary human gut organoids to capture multiple quantitative pathway readouts

Disruptions in the gut epithelial barrier can lead to the development of chronic indications such as inflammatory bowel disease (IBD). Historically, barrier function has been assessed in cancer cell lines, which do not contain all human intestinal cell types, leading to poor translatability. To brid...

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Detalles Bibliográficos
Autores principales: Wright, Charles W., Li, Naomi, Shaffer, Lynsey, Hill, Armetta, Boyer, Nicolas, Alves, Stephen E., Venkataraman, Sriraman, Biswas, Kaustav, Lieberman, Linda A., Mohammadi, Sina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541891/
https://www.ncbi.nlm.nih.gov/pubmed/37773535
http://dx.doi.org/10.1038/s41598-023-43656-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541891/
https://www.ncbi.nlm.nih.gov/pubmed/37773535
http://dx.doi.org/10.1038/s41598-023-43656-z

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