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Establishment of a 96-well transwell system using primary human gut organoids to capture multiple quantitative pathway readouts
Disruptions in the gut epithelial barrier can lead to the development of chronic indications such as inflammatory bowel disease (IBD). Historically, barrier function has been assessed in cancer cell lines, which do not contain all human intestinal cell types, leading to poor translatability. To brid...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541891/ https://www.ncbi.nlm.nih.gov/pubmed/37773535 http://dx.doi.org/10.1038/s41598-023-43656-z |