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An engineered periosteum for efficient delivery of rhBMP-2 and mesenchymal progenitor cells during bone regeneration

During bone regeneration, the periosteum acts as a carrier for key regenerative cues, delivering osteochondroprogenitor cells and crucial growth factors to the injured bone. We developed a biocompatible, 3D polycaprolactone (PCL) melt electro-written membrane to act as a mimetic periosteum. Poly (et...

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Detalles Bibliográficos
Autores principales: Romero-Torrecilla, Juan Antonio, Lamo-Espinosa, José María, Ripalda-Cemboráin, Purificación, López-Martínez, Tania, Abizanda, Gloria, Riera-Álvarez, Luis, de Galarreta-Moriones, Sergio Ruiz, López-Barberena, Asier, Rodríguez-Flórez, Naiara, Elizalde, Reyes, Jayawarna, Vineetha, Valdés-Fernández, José, de Anleo, Miguel Echanove-González, Childs, Peter, de Juan-Pardo, Elena, Salmeron-Sanchez, Manuel, Prósper, Felipe, Muiños-López, Emma, Granero-Moltó, Froilán
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10541910/
https://www.ncbi.nlm.nih.gov/pubmed/37773177
http://dx.doi.org/10.1038/s41536-023-00330-2