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In-vitro Modulation of mTOR-HIF-1α Axis by TLR7/8 Agonist (Resiquimod) in B-Chronic Lymphocytic Leukemia

Targeting toll-like receptors (TLRs), via TLR agonists, has been implicated in the regulation of immunometabolism. B-chronic lymphocytic leukemia (B-CLL) represents a suitable model for B-cell derived malignancies with shifted metabolic adaptations. Several signaling pathways have been found to be c...

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Detalles Bibliográficos
Autores principales: Hanafy, Rana M., Demian, Soheir R., Abou-Shamaa, Lobna A., Ghallab, O., Osman, Eman M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer India 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542076/
https://www.ncbi.nlm.nih.gov/pubmed/37786827
http://dx.doi.org/10.1007/s12288-023-01649-y