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In-vitro Modulation of mTOR-HIF-1α Axis by TLR7/8 Agonist (Resiquimod) in B-Chronic Lymphocytic Leukemia
Targeting toll-like receptors (TLRs), via TLR agonists, has been implicated in the regulation of immunometabolism. B-chronic lymphocytic leukemia (B-CLL) represents a suitable model for B-cell derived malignancies with shifted metabolic adaptations. Several signaling pathways have been found to be c...
Autores principales: | Hanafy, Rana M., Demian, Soheir R., Abou-Shamaa, Lobna A., Ghallab, O., Osman, Eman M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer India
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542076/ https://www.ncbi.nlm.nih.gov/pubmed/37786827 http://dx.doi.org/10.1007/s12288-023-01649-y |
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