Massively parallel in vivo Perturb-seq reveals cell type-specific transcriptional networks in cortical development

Systematic analysis of gene function across diverse cell types in vivo is hindered by two challenges: obtaining sufficient cells from live tissues and accurately identifying each cell’s perturbation in high-throughput single-cell assays. Leveraging AAV’s versatile cell type tropism and high labeling...

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Detalles Bibliográficos
Autores principales: Zheng, Xinhe, Wu, Boli, Liu, Yuejia, Simmons, Sean K., Kim, Kwanho, Clarke, Grace S., Ashiq, Abdullah, Park, Joshua, Wang, Zhilin, Tong, Liqi, Wang, Qizhao, Xu, Xiangmin, Levin, Joshua Z., Jin, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542124/
https://www.ncbi.nlm.nih.gov/pubmed/37790302
http://dx.doi.org/10.1101/2023.09.18.558077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542124/
https://www.ncbi.nlm.nih.gov/pubmed/37790302
http://dx.doi.org/10.1101/2023.09.18.558077

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