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Massively parallel in vivo Perturb-seq reveals cell type-specific transcriptional networks in cortical development

Systematic analysis of gene function across diverse cell types in vivo is hindered by two challenges: obtaining sufficient cells from live tissues and accurately identifying each cell’s perturbation in high-throughput single-cell assays. Leveraging AAV’s versatile cell type tropism and high labeling...

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Detalles Bibliográficos
Autores principales:	Zheng, Xinhe, Wu, Boli, Liu, Yuejia, Simmons, Sean K., Kim, Kwanho, Clarke, Grace S., Ashiq, Abdullah, Park, Joshua, Wang, Zhilin, Tong, Liqi, Wang, Qizhao, Xu, Xiangmin, Levin, Joshua Z., Jin, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542124/ https://www.ncbi.nlm.nih.gov/pubmed/37790302 http://dx.doi.org/10.1101/2023.09.18.558077

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