Single-cell Herpes Simplex Virus type-1 infection of neurons using drop-based microfluidics reveals heterogeneous replication kinetics

Single-cell analyses of viral infections often reveal heterogeneity that is not detected by traditional population-level studies. This study applies drop-based microfluidics to investigate the dynamics of HSV-1 infection of neurons at the single-cell level. We used micron-scale Matrigel beads, terme...

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Detalles Bibliográficos
Autores principales: Fredrikson, Jacob P., Domanico, Luke F., Pratt, Shawna L., Loveday, Emma K., Taylor, Matthew P., Chang, Connie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542126/
https://www.ncbi.nlm.nih.gov/pubmed/37790515
http://dx.doi.org/10.1101/2023.09.18.558333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542126/
https://www.ncbi.nlm.nih.gov/pubmed/37790515
http://dx.doi.org/10.1101/2023.09.18.558333

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