Cardiomyocyte-specific Loss of Glutamyl-prolyl-tRNA Synthetase Leads to Disturbed Protein Homeostasis and Dilated Cardiomyopathy

Glutamyl-prolyl-tRNA synthetase (EPRS1), an aminoacyl-tRNA synthetase (ARS) ligating glutamic acid and proline to their corresponding tRNAs, plays an essential role in decoding proline codons during translation elongation. The physiological function of EPRS1 in cardiomyocytes (CMs) and the potential...

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Detalles Bibliográficos
Autores principales: Wu, Jiangbin, Hollinger, Jared, Bonanno, Emily, Jiang, Feng, Yao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542137/
https://www.ncbi.nlm.nih.gov/pubmed/37790482
http://dx.doi.org/10.1101/2023.09.19.558539

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542137/
https://www.ncbi.nlm.nih.gov/pubmed/37790482
http://dx.doi.org/10.1101/2023.09.19.558539

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