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Prrx1-driven LINC complex disruption in vivo does not significantly alter bone properties in 8-week male mice nor after 6-weeks voluntary wheel running

The Linker of Nucleoskeleton and Cytoskeleton (LINC) complex serves to connect the nuclear envelope and the cytoskeleton, influencing cellular processes such as nuclear arrangement, architecture, and mechanotransduction. The role LINC plays in mechanotransduction pathways in bone progenitor cells ha...

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Detalles Bibliográficos
Autores principales: Birks, Scott, Howard, Sean, Wright, Christian S., O’Rourke, Caroline, Lau, Anthony, Thompson, William R., Uzer, Gunes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542150/
https://www.ncbi.nlm.nih.gov/pubmed/37790521
http://dx.doi.org/10.1101/2023.09.22.559054