Cargando…

C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

Invertebrates use the endoribonuclease Dicer to cleave viral dsRNA during antiviral defense, while vertebrates use RIG-I-like Receptors (RLRs), which bind viral dsRNA to trigger an interferon response. While some invertebrate Dicers act alone during antiviral defense, C. elegans Dicer acts in a comp...

Descripción completa

Detalles Bibliográficos
Autores principales: Consalvo, Claudia D., Aderounmu, Adedeji M., Donelick, Helen M., Aruscavage, P. Joe, Eckert, Debra M., Shen, Peter S., Bass, Brenda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542151/
https://www.ncbi.nlm.nih.gov/pubmed/37790392
http://dx.doi.org/10.1101/2023.09.21.558868