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C. elegans Dicer acts with the RIG-I-like helicase DRH-1 and RDE-4 to cleave dsRNA

Invertebrates use the endoribonuclease Dicer to cleave viral dsRNA during antiviral defense, while vertebrates use RIG-I-like Receptors (RLRs), which bind viral dsRNA to trigger an interferon response. While some invertebrate Dicers act alone during antiviral defense, C. elegans Dicer acts in a comp...

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Detalles Bibliográficos
Autores principales:	Consalvo, Claudia D., Aderounmu, Adedeji M., Donelick, Helen M., Aruscavage, P. Joe, Eckert, Debra M., Shen, Peter S., Bass, Brenda L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542151/ https://www.ncbi.nlm.nih.gov/pubmed/37790392 http://dx.doi.org/10.1101/2023.09.21.558868

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