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Role Of The C-C Motif Chemokine Ligand 5 (CCL5) And Its Receptor, C-C Motif Chemokine Receptor 5 (CCR5) In The Genesis Of Aldosterone-induced Hypertension, Vascular Dysfunction, And End-organ Damage

BACKGROUND: Aldosterone, a mineralocorticoid steroid hormone, has been described to initiate cardiovascular diseases by triggering exacerbated sterile vascular inflammation. The functions of C-C Motif Chemokine Ligand 5 (CCL5) and its receptor, C-C Motif Chemokine Receptor 5 (CCR5), are well known i...

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Detalles Bibliográficos
Autores principales: Costa, Rafael M., Cerqueira, Débora M., Bruder-Nascimento, Ariane, Alves, Juliano V., Awata, Wanessa A.C., Singh, Shubhnita, Kufner, Alexander, Cifuentes-Pagano, Eugenia, Pagano, Patrick J., Ho, Jacqueline, Bruder-Nascimento, Thiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542153/
https://www.ncbi.nlm.nih.gov/pubmed/37790434
http://dx.doi.org/10.1101/2023.09.22.558020