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Division of labor among H3K4 Methyltransferases Defines Distinct Facets of Homeostatic Plasticity

Heterozygous mutations in any of the six H3K4 methyltransferases (KMT2s) result in monogenic neurodevelopmental disorders, indicating nonredundant yet poorly understood roles of this enzyme family in neurodevelopment. Recent evidence suggests that histone methyltransferase activity may not be centra...

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Detalles Bibliográficos
Autores principales: Tsukahara, Takao, Kethireddy, Saini, Bonefas, Katherine, Chen, Alex, Sutton, Brendan LM, Dou, Yali, Iwase, Shigeki, Sutton, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542164/
https://www.ncbi.nlm.nih.gov/pubmed/37790395
http://dx.doi.org/10.1101/2023.09.20.558734