Phenotypic defects from the expression of wild-type and pathogenic TATA-binding proteins in new Drosophila models of Spinocerebellar Ataxia Type 17

Spinocerebellar Ataxia Type 17 (SCA17) is the most recently identified member of the polyglutamine (polyQ) family of disorders, resulting from abnormal CAG/CAA expansion in the TATA box-binding protein (TBP), an initiation factor essential for of all eukaryotic transcription. A largely autosomal dom...

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Detalles Bibliográficos
Autores principales: Patel, Nikhil, Alam, Nadir, Libohova, Kozeta, Dulay, Ryan, Todi, Sokol V, Sujkowski, Alyson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Genetic Models of Rare Diseases
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542169/
https://www.ncbi.nlm.nih.gov/pubmed/37551423
http://dx.doi.org/10.1093/g3journal/jkad180

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542169/
https://www.ncbi.nlm.nih.gov/pubmed/37551423
http://dx.doi.org/10.1093/g3journal/jkad180

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