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Glutamate neurotransmission from leptin receptor cells is required for typical puberty and reproductive function in female mice

The hypothalamic ventral premammillary nucleus (PMv) is a glutamatergic nucleus essential for the metabolic control of reproduction. However, conditional deletion of leptin receptor (LepRb) in vesicular glutamate transporter 2 (Vglut2) expressing neurons results in virtually no reproductive deficits...

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Detalles Bibliográficos
Autores principales: de Miera, Cristina Sáenz, Bellefontaine, Nicole, Allen, Susan J., Myers, Martin G., Elias, Carol F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542178/
https://www.ncbi.nlm.nih.gov/pubmed/37790549
http://dx.doi.org/10.1101/2023.09.21.558865