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ATR-binding lncRNA ScaRNA2 promotes cancer resistance through facilitating efficient DNA end resection during homologous recombination repair

BACKGROUND: Our previous study first showed that ATR-binding long noncoding RNA (lncRNA) is necessary for ATR function and promotes cancer resistance. However, the specific lncRNAs instrumental in ATR activation remain largely unclear, which limits our comprehensive understanding of this critical bi...

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Detalles Bibliográficos
Autores principales: Chen, Yuanyuan, Shen, Hui, Liu, Tingting, Cao, Kun, Wan, Zhijie, Du, Zhipeng, Wang, Hang, Yu, Yue, Ma, Shengzhe, Lu, Edward, Zhang, Wei, Cai, Jianming, Gao, Fu, Yang, Yanyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542231/
https://www.ncbi.nlm.nih.gov/pubmed/37775817
http://dx.doi.org/10.1186/s13046-023-02829-4