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Wnt/β-catenin pathway is a key signaling pathway to trastuzumab resistance in gastric cancer cells
BACKGROUND: Trastuzumab is the only approved target agent for the first-line treatment of human epidermal growth factor receptor-2 (HER-2) positive gastric cancer; however, trastuzumab resistance is a major problem in clinical practice. To comprehend the mechanism of trastuzumab resistance, we focus...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542239/ https://www.ncbi.nlm.nih.gov/pubmed/37773114 http://dx.doi.org/10.1186/s12885-023-11447-4 |