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Cryo-electron tomography of intact cardiac muscle reveals myosin binding protein-C linking myosin and actin filaments

Myosin binding protein C (MyBP-C) is an accessory protein of the thick filament in vertebrate cardiac muscle arranged over 9 stripes of intervals of 430 Å in each half of the A-band in the region called the C-zone. Mutations in cardiac MyBP-C are a leading cause of hypertrophic cardiomyopathy the me...

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Detalles Bibliográficos
Autores principales: Huang, Xinrui, Torre, Iratxe, Chiappi, Michele, Yin, Zhan, Vydyanath, Anupama, Cao, Shuangyi, Raschdorf, Oliver, Beeby, Morgan, Quigley, Bonnie, de Tombe, Pieter P., Liu, Jun, Morris, Edward P., Luther, Pradeep K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542292/
https://www.ncbi.nlm.nih.gov/pubmed/37115473
http://dx.doi.org/10.1007/s10974-023-09647-3