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Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio

Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are highly conserved across species. We have used cryo-EM to study the three-dimensional structure of the zebrafish cardiac thin and actin filaments. With 70% of human genes having an...

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Detalles Bibliográficos
Autores principales: Bradshaw, Marston, Squire, John M., Morris, Edward, Atkinson, Georgia, Richardson, Rebecca, Lees, Jon, Caputo, Massimo, Bigotti, Giulia M., Paul, Danielle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542308/
https://www.ncbi.nlm.nih.gov/pubmed/37480427
http://dx.doi.org/10.1007/s10974-023-09653-5