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Zebrafish as a model for cardiac disease; Cryo-EM structure of native cardiac thin filaments from Danio Rerio
Actin, tropomyosin and troponin, the proteins that comprise the contractile apparatus of the cardiac thin filament, are highly conserved across species. We have used cryo-EM to study the three-dimensional structure of the zebrafish cardiac thin and actin filaments. With 70% of human genes having an...
Autores principales: | Bradshaw, Marston, Squire, John M., Morris, Edward, Atkinson, Georgia, Richardson, Rebecca, Lees, Jon, Caputo, Massimo, Bigotti, Giulia M., Paul, Danielle M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542308/ https://www.ncbi.nlm.nih.gov/pubmed/37480427 http://dx.doi.org/10.1007/s10974-023-09653-5 |
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