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Localized conditional induction of brain arteriovenous malformations in a mouse model of hereditary hemorrhagic telangiectasia

BACKGROUND: Longitudinal mouse models of brain arteriovenous malformations (AVMs) are crucial for developing novel therapeutics and pathobiological mechanism discovery underlying brain AVM progression and rupture. The sustainability of existing mouse models is limited by ubiquitous Cre activation, w...

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Detalles Bibliográficos
Autores principales: Scherschinski, Lea, Han, Chul, Kim, Yong Hwan, Winkler, Ethan A., Catapano, Joshua S., Schriber, Tyler D., Vajkoczy, Peter, Lawton, Michael T., Oh, S. Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542309/
https://www.ncbi.nlm.nih.gov/pubmed/37219736
http://dx.doi.org/10.1007/s10456-023-09881-w