Testing for pharmacogenomic predictors of ppRNFL thinning in individuals exposed to vigabatrin

BACKGROUND: The anti-seizure medication vigabatrin (VGB) is effective for controlling seizures, especially infantile spasms. However, use is limited by VGB-associated visual field loss (VAVFL). The mechanisms by which VGB causes VAVFL remains unknown. Average peripapillary retinal nerve fibre layer...

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Detalles Bibliográficos
Autores principales: Boothman, Isabelle, Clayton, Lisa M., McCormack, Mark, Driscoll, Alexandra McKibben, Stevelink, Remi, Moloney, Patrick, Krause, Roland, Kunz, Wolfram S., Diehl, Sarah, O’Brien, Terence J., Sills, Graeme J., de Haan, Gerrit-Jan, Zara, Federico, Koeleman, Bobby P., Depondt, Chantal, Marson, Anthony G., Stefansson, Hreinn, Stefansson, Kari, Craig, John, Johnson, Michael R., Striano, Pasquale, Lerche, Holger, Furney, Simon J., Delanty, Norman, Sisodiya, Sanjay M., Cavalleri, Gianpiero L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542409/
https://www.ncbi.nlm.nih.gov/pubmed/37790589
http://dx.doi.org/10.3389/fnins.2023.1156362

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542409/
https://www.ncbi.nlm.nih.gov/pubmed/37790589
http://dx.doi.org/10.3389/fnins.2023.1156362

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