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Activity-dependent development of the body’s touch receptors

We report a role for activity in the development of the primary sensory neurons that detect touch. Genetic deletion of Piezo2, the principal mechanosensitive ion channel in somatosensory neurons, caused profound changes in the formation of mechanosensory end organ structures and altered somatosensor...

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Detalles Bibliográficos
Autores principales: Santiago, Celine, Sharma, Nikhil, Africawala, Nusrat, Siegrist, Julianna, Handler, Annie, Tasnim, Aniqa, Anjum, Rabia, Turecek, Josef, Lehnert, Brendan P., Renauld, Sophia, Nolan-Tamariz, Michael, Iskols, Michael, Magee, Alexandra R., Paradis, Suzanne, Ginty, David D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542488/
https://www.ncbi.nlm.nih.gov/pubmed/37790437
http://dx.doi.org/10.1101/2023.09.23.559109