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Acetylcholine signaling in the medial prefrontal cortex mediates the ability to learn an active avoidance response following learned helplessness training

Increased brain levels of acetylcholine (ACh) are observed in subsets of patients with depression and increasing ACh levels chronically can precipitate stress-related behaviors in humans and animals. Conversely, optimal ACh levels are required for cognition and memory. We hypothesize that ACh signal...

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Detalles Bibliográficos
Autores principales: Abdulla, Zuhair I., Mineur, Yann S., Crouse, Richard B., Etherington, Ian M., Yousuf, Hanna, Na, Jessica J., Picciotto, Marina R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542494/
https://www.ncbi.nlm.nih.gov/pubmed/37790481
http://dx.doi.org/10.1101/2023.09.23.559126