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Simultaneous estimation of gene regulatory network structure and RNA kinetics from single cell gene expression

Cells respond to environmental and developmental stimuli by remodeling their transcriptomes through regulation of both mRNA transcription and mRNA decay. A central goal of biology is identifying the global set of regulatory relationships between factors that control mRNA production and degradation a...

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Detalles Bibliográficos
Autores principales: Jackson, Christopher A, Beheler-Amass, Maggie, Tjärnberg, Andreas, Suresh, Ina, Hickey, Angela Shang-mei, Bonneau, Richard, Gresham, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542544/
https://www.ncbi.nlm.nih.gov/pubmed/37790443
http://dx.doi.org/10.1101/2023.09.21.558277