A Monte Carlo simulation study comparing the up and down, biased-coin up and down and continual reassessment methods used to estimate an effective dose (ED(95) or ED(90)) in anaesthesiology research

BACKGROUND: Dose-finding studies in anaesthesiology aim to target the effective dose (ED) of an anaesthetic agent in a specific population. The common dose-finding designs used are the up and down method (UDM), the biased-coin up and down (BCD), and the continual reassessment method (CRM). Although...

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Detalles Bibliográficos
Autores principales: Fils, Jean-François, Kapessidou, Panayota, Van der Linden, Philippe, Guntz, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542596/
https://www.ncbi.nlm.nih.gov/pubmed/37790993
http://dx.doi.org/10.1016/j.bjao.2023.100225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542596/
https://www.ncbi.nlm.nih.gov/pubmed/37790993
http://dx.doi.org/10.1016/j.bjao.2023.100225

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