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WNT16b promotes the proliferation and self‐renewal of human limbal epithelial stem/progenitor cells via activating the calcium/calcineurin A/NFATC2 pathway

Our previous finding revealed that WNT16b promoted the proliferation of human limbal epithelial stem cells (hLESCs) through a β‐catenin independent pathway. Here, we aimed to explore its underlying molecular mechanism and evaluate its potential in the treatment of limbal stem cell deficiency (LSCD)....

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Detalles Bibliográficos
Autores principales: Wan, Xichen, Zhao, Songjiao, Dai, Yiqin, Zhang, Jing, Shen, Yan, Gong, Lan, Le, Qihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542615/
https://www.ncbi.nlm.nih.gov/pubmed/36974338
http://dx.doi.org/10.1111/cpr.13460