Constitutively activated AMPKα1 protects against skeletal aging in mice by promoting bone‐derived IGF‐1 secretion

Senile osteoporosis is characterized by age‐related bone loss and bone microarchitecture deterioration. However, little is known to date about the mechanism that maintains bone homeostasis during aging. In this study, we identify adenosine monophosphate‐activated protein kinase alpha 1 (AMPKα1) as a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yiqi, Yuan, Kai, Liu, Yihao, Wang, Qishan, Lin, Yixuan, Yang, Shengbing, Huang, Kai, Kan, Tianyou, Zhang, Yuxin, Xu, Mingming, Yu, Zhifeng, Fan, Qiming, Wang, Yugang, Li, Hanjun, Tang, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542616/
https://www.ncbi.nlm.nih.gov/pubmed/37042047
http://dx.doi.org/10.1111/cpr.13476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542616/
https://www.ncbi.nlm.nih.gov/pubmed/37042047
http://dx.doi.org/10.1111/cpr.13476

Ejemplares similares