PR‐DUB safeguards Polycomb repression through H2AK119ub1 restriction

Polycomb group (PcG) proteins are critical chromatin regulators for cell fate control. The mono‐ubiquitylation on histone H2AK119 (H2AK119ub1) is one of the well‐recognized mechanisms for Polycomb repressive complex 1 (PRC1)‐mediated transcription repression. Unexpectedly, the specific H2AK119 deubi...

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Detalles Bibliográficos
Autores principales: Li, Rui, Huang, Dandan, Zhao, Yingying, Yuan, Ye, Sun, Xiaoyu, Dai, Zhongye, Huo, Dawei, Liu, Xiaozhi, Helin, Kristian, Li, Mulin Jun, Wu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542648/
https://www.ncbi.nlm.nih.gov/pubmed/36959757
http://dx.doi.org/10.1111/cpr.13457

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10542648/
https://www.ncbi.nlm.nih.gov/pubmed/36959757
http://dx.doi.org/10.1111/cpr.13457

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